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    Prothiaden (Dosulepin Hydrochloride) Tablet is a tricyclic antidepressant manufactured by Abbott and has anxiolytic properties.

    It comprises Dosulepin hydrochloride which is a white to fainty yellow crystalline powder and is almost odorless. The compound is soluble in water, chloroform, and alcohol but is almost insoluble in ether.

    Usage: This medicine is indicated in the treatment of symptoms of depressive illness, especially where an anti-anxiety effect is required. Due to its toxicity in overdose, it should only be used in patients intolerant of or unresponsive to alternative treatment options.

    Each pack contains: Each pack contains 3×10 tablets of 75mg.



    Each film-coated tablet contains Dosulepin Hydrochloride B.P. 75mg.


    1-2 tablets daily or as directed by the Physician.

    Adults: initially administer 75mg daily in divided doses or as a single dose at night, increasing to 10mg/day.

    Elderly: the recommended dose is 50 to 75mg daily. Elderly patients may require a lower starting dose and slow dose escalation.

    Children: the use of this medicine in children has not been studied.

    Side effects:

    This medicine is excreted in human milk. Breastfeeding should be discontinued during treatment with dosulepin.

    The following adverse reactions although not necessarily all reported with this medicine, have occurred with other tricyclic antidepressants.

    • Blood and lymphatic system disorder
    • Human immune system disorder
    • Cardiac and vascular disorder
    • Gastrointestinal disorder
    • Hepatobiliary disorders
    • Skin and subcutaneous disorder
    • Reproductive system and breast disorder


    Prothiaden back

    Protect from excessive heat, light, and moisture.

    Keep out of reach of children.

    To be dispensed on the prescription of a registered medical practitioner.


    You can contact the manufacturer at

    Buy this medicine online at


    By Javairia Israr

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